The synthesis and characterization of novel platinum(II) complexes containing bulky aromatic groups

Abstract

Six iminopyridine ligands were prepared from the condensation of 6-methyl-2-pyridinecarboxyaldehyde and the corresponding primary amines containing bulky cycloalkyl groups. Addition of these ligands to [PtCl2(coe)]2 (coe=cis-cyclooctene) gave the desired platinum(II) coordination complexes in moderate to high yields. All compounds were fully characterized using FT-IR and multinuclear NMR spectroscopy. Solid compounds were subjected to melting point analysis. Elemental analysis (EA) was performed on three of the platinum(II) complexes. Future work will involve completing elemental analysis studies and performing biological testing. X-ray diffraction studies must be performed to support the existing characterization data.